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Pure Tone Aesthetics Polynucleotide Moisturising Cream

Pure Tone Aesthetics Polynucleotide Moisturising Cream

Designed for Skin Showing Visible Signs of Ageing

A daily anti-ageing moisturiser designed to support skin showing visible signs of ageing — including fine lines, dryness, loss of firmness, and dullness.

Powered by polynucleotides (PDRN), multi-molecular hyaluronic acid, and niacinamide, it helps deeply hydrate, strengthen the skin barrier, and improve overall skin quality with consistent morning and evening use.

Developed for clinic-led skincare and designed for consistent daily home use.

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Normaler Preis £39.99 GBP
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Hydration that supports skin quality — not just surface softness

This polynucleotide moisturising cream is designed to do more than provide temporary softness. Its purpose is to support hydration, comfort, and barrier function day after day — helping skin look smoother, more resilient, and visibly healthier over time.

By combining advanced hydration systems with skin-supporting actives, including polynucleotides (PDRN), niacinamide, and ginseng-derived components, it fits naturally into a daily routine alongside cleanser and serum. The focus is on dependable, cumulative improvement through consistent use, rather than short-term cosmetic effects.

Pure Tone Aesthetics Polynucleotide anti-ageing moisturiser in bathroom with the lid off

Advanced hydration and barrier support for ageing skin

Lightweight, whipped-cream-like texture that absorbs easily and layers seamlessly with serums, SPF, and makeup.

  • Delivers deep, long-lasting hydration to ageing skin
  • Helps support the skin barrier and moisture retention
  • Softens the appearance of fine lines and wrinkles caused by dryness
  • Improves the look of skin smoothness and elasticity over time
  • Suitable for consistent daily use, morning and evening

Developed for Clinic-Led Skincare, Suitable for Daily Home Use

“In clinic, we look for products that support skin quality and barrier health over time, not just immediate cosmetic effects. This moisturiser is formulated with skin-compatible actives that fit well into both professional treatment plans and daily home routines”

Joolia Gilvey | Nurse Prescriber and Owner of The Clinic Norwich

Jar of Pure Tone anti-aging polynucleotide moisturiser on a white bathroom surface with a plant in the background

How it works: multi-level hydration and skin support

This moisturising cream works by supporting the skin’s natural hydration processes and barrier function, rather than masking dryness at the surface.

Multiple forms of hyaluronic acid help attract and retain moisture at different levels of the skin, supporting both immediate comfort and longer-term hydration. Polynucleotides (PDRN) and niacinamide help support overall skin condition and resilience, while ginseng-derived and soothing actives contribute to skin balance and comfort.

With consistent use, the formula helps maintain moisture levels, support barrier integrity, and improve the visible quality of the skin over time.

Who this moisturiser is designed for

As skin ages, changes in hydration, elasticity, and barrier strength can become more noticeable. Fine lines deepen, skin feels less firm, and radiance can fade — often accelerated by environmental exposure and reduced moisture retention.

This moisturiser is designed for skin showing visible signs of ageing, helping to support hydration, skin comfort, and overall skin quality with consistent daily use.

  • Visible Fine Lines and Wrinkles

    Skin where fine lines and wrinkles are clearly visible, often appearing more pronounced when hydration levels drop and elasticity declines over time.

  • Loss of Firmness and Skin Elasticity

    Skin that feels less supported or toned, with a looser appearance and reduced bounce as natural structural support diminishes.

  • Dull, Tired or Age-Fatigued Skin

    Skin that looks flat or tired rather than fresh and radiant, commonly linked to dehydration, environmental stress, and the ageing process.

  • Dryness and Reduced Moisture Retention

    Skin that struggles to retain moisture as it ages, leading to tightness, rough texture, and fine lines appearing more visible throughout the day.

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Key Active Ingredients

This formula combines carefully selected, skin-compatible actives commonly used in advanced skincare formulations chosen for their role in supporting hydration, barrier function, and overall skin condition. Each ingredient has a specific purpose within the formula, contributing to visible improvements in skin comfort, smoothness, and resilience when used consistently as part of a daily routine.

Polynucleotides (PDRN)

What it is

DNA-derived molecules commonly used in advanced skincare formulations to support overall skin condition and recovery.

Why included

Selected for its role in supporting skin quality and resilience, particularly in skin showing visible signs of ageing.

What it supports
  • Skin comfort and recovery
  • Improved skin resilience
  • The appearance of smoother, more elastic skin

Multi-Molecular Hyaluronic Acid Complex

What it is

A sophisticated blend of hyaluronic acid in multiple molecular weights, including Sodium Hyaluronate, Hydrolysed Hyaluronic Acid, Crosspolymer HA, and Acetylated HA.

Why included

Different molecular sizes allow hydration to work at multiple levels of the skin, delivering both immediate surface plumping and longer-lasting moisture retention.

What it supports
  • Deep, multi-level hydration
  • Improved skin suppleness and comfort
  • Reduced appearance of dehydration lines

Niacinamide (Vitamin B3)

What it is

A well-studied, multi-functional vitamin recognised for its barrier-supporting and skin-balancing properties.

Why included

Niacinamide helps strengthen the skin barrier, improve tone and texture, and support smoother, more even-looking skin.

What it supports
  • Enhanced barrier function and moisture retention
  • Improved skin texture and clarity
  • Reduced appearance of fine lines over time

Panax Ginseng Vesicles

What it is

Ginseng-derived vesicles designed to enhance delivery of bioactive compounds to the skin.

Why included

Ginseng is valued in skincare for supporting skin vitality and improving the appearance of tired, dull, or ageing skin.

What it supports
  • Skin vitality and radiance
  • Improved appearance of elasticity
  • Support for stressed or environmentally challenged skin

Beta-Glucan

What it is

A naturally derived polysaccharide known for its soothing and skin-conditioning properties.

Why included

Beta-glucan helps calm the skin while supporting hydration and reinforcing the skin’s protective barrier.

What it supports
  • Skin comfort and resilience
  • Reduced appearance of redness or sensitivity
  • Barrier recovery and moisture balance

Adenosine & Allantoin

What it is

Skin-conditioning ingredients commonly used to support comfort, smoothness, and visible anti-ageing benefits.

Why included

These ingredients work together to help soften the skin, improve texture, and support a smoother-looking complexion.

What it supports
  • Reduced appearance of fine lines
  • Smoother skin texture
  • Improved skin comfort and softness

How to Use This Moisturiser

This moisturiser is designed to fit easily into both morning and evening skincare routines, whether you keep things simple or use additional skincare tools commonly found in clinic-led routines. It can be applied on its own or after serums, and is suitable for daily use.

Select the routine below that best reflects how you care for your skin and follow the recommended order of steps for consistent, long-term results.

Choose your routine to see the recommended order of steps

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woman cleansing her face with foaming cleansing gel

Step 1: Cleanse

Begin with clean skin to remove impurities and prepare the skin for the steps that follow.

Use your preferred facial cleanser, massaging gently and rinsing thoroughly.

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Step 2: Apply polynucleotide serum

Apply the Pure Tone Aesthetics Polynucleotide Serum to the face and neck, gently pressing it into the skin until fully absorbed.

Using the serum before moisturising helps support hydration and overall skin quality.

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Lady applying moisturiser with a big smile on her face

Step 3: Moisturise

Apply the Pure Tone Aesthetics Polynucleotide Moisturising Cream to the face and neck as the final step in your routine.

Massage gently until absorbed to help lock in hydration and maintain skin comfort throughout the day or night.

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woman cleansing her face with foaming cleansing gel

Step 1: Cleanse

Start with clean skin to remove impurities and prepare the skin for the steps that follow. Use your preferred facial cleanser — a gentle foaming cleanser works particularly well for daily use.

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Radiance Pod skincare device being held in hand

Step 2: Use Radiance Pod

Apply the Pure Tone Aesthetics Conductor and Gliding Gel to clean skin, then use Radiance Pod following the device guidance for your chosen treatment mode.

Once finished, gently wipe away any excess gel before applying serums or moisturiser, helping prepare the skin for the products that follow.

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Step 3: Apply polynucleotide serum

Apply the Pure Tone Aesthetics Polynucleotide Serum to the face and neck, gently pressing it into the skin until fully absorbed.

Using the polynucleotide serum before moisturising helps support hydration and overall skin quality, allowing the moisturiser to work more effectively as the final step.

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Lady applying moisturiser with a big smile on her face

Step 4: Moisturise

Apply the Pure Tone Aesthetics Polynucleotide Moisturising Cream to the face and neck as the final step in your routine.

Gently massage into the skin until fully absorbed to help lock in hydration, support the skin barrier, and maintain comfort and skin quality throughout the day or night.

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woman cleansing her face with foaming cleansing gel

Step 1: Cleanse

Begin with clean, dry skin to remove impurities and ensure the LED treatment is applied to bare skin.

Use your preferred facial cleanser, rinsing thoroughly and gently patting the skin dry.

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Step 2: Apply serum

Apply a thin, even layer of serum to the face and neck.

You can use either the Pure Tone Aesthetics Radiance Ampoule or the Pure Tone Aesthetics Polynucleotide Serum, depending on your skin’s needs and preferences.

Allow the serum to absorb before using the LED face mask.

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Step 3: Use the LED face mask

Use the Pure Tone Aesthetics LED face mask according to the device guidance and your chosen light setting.

Ensure the mask sits comfortably and evenly on the skin for the duration of the treatment.

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Lady applying moisturiser with a big smile on her face

Step 4: Moisturise

After completing the LED treatment, apply the Pure Tone Aesthetics Polynucleotide Moisturising Cream to the face and neck.

Gently massage until fully absorbed to help support hydration, skin comfort, and barrier function as the final step in your routine.

What to Expect with Consistent Use

  • Immediate: skin feels more comfortable and hydrated
  • Over time: skin looks smoother, more resilient, and more even
  • With continued use: visible improvement in overall skin quality

Frequently Asked Questions

What is the Polynucleotide Moisturising Cream and what does it do?

The Pure Tone Aesthetics Polynucleotide Moisturising Cream is a daily moisturiser designed to provide deep hydration, support the skin barrier, and improve the visible quality of the skin over time. It helps maintain skin comfort while supporting the appearance of smoother texture, elasticity, and fine lines with consistent use.

Can this moisturiser be used morning and night?

Yes. This moisturiser is suitable for both morning and evening use. While it can be used during the day, many people prefer applying it in the evening, when skin naturally focuses on renewal overnight.

Is this moisturiser suitable for all skin types, including sensitive skin?

This moisturiser is designed for skin that is beginning to show fine lines, loss of smoothness, and a dull or tired appearance. It is ideal for those looking to support hydration, skin elasticity, and overall skin quality as part of an anti-ageing skincare routine.

The formula is suitable for all skin types, including normal, combination, and dry skin.

If you have sensitive or reactive skin, we recommend introducing new products gradually. As with all skincare products, a patch test is advised before first use.

Can I use this moisturiser as part of a skincare routine with serums, devices, or masks?

Yes. The moisturiser is designed to work as the final step in a skincare routine. It can be used after cleansing and serum application, and after skincare devices or LED masks once any gels or residues have been removed.

Is this moisturiser vegan and cruelty free?

Yes. The Pure Tone Aesthetics Polynucleotide Moisturising Cream is vegan and cruelty free. It is not tested on animals and does not contain animal-derived ingredients.

Does this moisturiser contain fragrance or essential oils?

No. The formula does not contain added fragrance or essential oils.

Are there any warnings or precautions I should be aware of?

  • For external use only.
  • Avoid direct contact with the eyes. If contact occurs, rinse thoroughly with water.
  • Do not apply to broken, irritated, or compromised skin.
  • Discontinue use if irritation occurs.
  • This product is intended for adult use only.
  • Store in a cool, dry place away from direct sunlight.

Is this moisturiser suitable during pregnancy or breastfeeding?

If you are pregnant, breastfeeding, or under medical supervision, we recommend seeking advice from a healthcare professional before introducing new skincare products.

What are the full ingredients (INCI)?

Ingredients (INCI):

Water, Glycerine, Butylene Glycol, Caprylic/Capric Triglyceride, Hydrogenated Polyisobutene, Niacinamide, Dimethicone, Isododecane, Stearic Acid, 1,2-Hexanediol, C14-22 Alcohols, Sorbitan Stearate, Cetearyl Alcohol, Dimethicone/Vinyl Dimethicone Crosspolymer, Dimethiconol, Carbomer, Arginine, C12-20 Alkyl Glucoside, Sodium Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Isohexadecane, Fragrance, Ethylhexylglycerin, Allantoin, Adenosine, Polysorbate 80, Disodium EDTA, Sorbitan Oleate, Sodium Hyaluronate, Glucose, Trehalose, Ascorbic Acid, Glutathione, Calcium Pantothenate, Sodium Starch Octenylsuccinate, Maltodextrin, Sodium DNA, Sodium Ascorbyl Phosphate, Pyridoxine HCl, Tocopheryl Acetate, Hyaluronic Acid, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Potassium Hyaluronate, Sodium Hyaluronate Crosspolymer, Beta-Glucan, Pentylene Glycol, Silica, Sodium Acetylated Hyaluronate, Hippophae Rhamnoides Fruit Extract, Panax Ginseng Vesicles, Pullulan.

Can I return this product if it has been opened?

For hygiene and safety reasons, opened or used skincare products cannot be returned once the seal has been broken, unless the product is faulty.

If your product arrives damaged or there is an issue with your order, please contact our customer care team before use so we can help.